ARTHROCHALASIA TYPE (Formerly EDS Type VIIB)
Congential hip dislocation has been present in all biochemically proven individuals with this type of EDS. Severe generalized joint hypermobility with recurrent subluxations are seen in individuals with this type of EDS. Other manifestations of this type omay include: skin hyperextensibility with easy bruising; tissue fragility including atrophic scars; muscle hypotonia; kyphoscoliosis and radiologically mild ostenopenia.

The Arthrochalasia Type is caused by mutations leading to deficient processing of the amino-terminal end of procs1(I)[type A] or procx2(I)[type B] chains of collagen type I. It is inherited in an autosomal dominnant manner. A skin biopsy can also diagnose this type of EDS.

Types of EDS Main Page